Data si locul nasterii:
Februarie 26, 1968, Falticeni, Romania
Nationalitate:
Roman
Adresa permanenta:
Str. Pacurari, Nr. 124, Bl. 583, Et. 6, Apt.23, Iasi R-6600, Romania
Educatie:
1982-1986 Liceul "Nicu-Gane" Falticeni, Romania
1987-1992 Facultatea de Fizica, Universitatea "Alexandru I. Cuza" Iasi, Romania
(Bachelor of science in Biofizica)
Studii doctorale la Universitatea "Karl-Franzens" (Graz, Austria). Gradul de "doctor in fizica" a fost acordat "magna cum laude", in 1997.
Cariera:
July 1992
Asistent de cercetare la Facultatea de Fizica, Departmentul de Biofizica, Universitatea "Alexandru I. Cuza", Iasi, Romania.
August 1992 - August 1993
In urma unui concurs international am obtinut o burse de aistent de cercetare, acordata de UNESCO, pentru a lucra la "Biological Research Center", Institute of Biophysics (Szeged, Hungary).
January 1994 - April 1994
Am urmat cursul european ERASMUS in "Medical Physics and Biomedical Engineering", la Universitatea Patras (Patras, Greece).
December 1994 - October 1997
Studii doctorale la Universitatea "Karl-Franzens" (Graz, Austria) sub indrumarea Prof. Wolfgang Schreibmayer.
October 1997 - August 1998
In data de 27 octombrie 1997, am sustinut in sedinta publica, la Universitatea "Karl-Franzens" (Graz, Austria) teza de doctorat "Gating modulation of a G protein activated, inwardly rectifying potassium channel by a cytosolic applied peptide". Dupa prezentare, mi-a fost acordat titlul de "doctor in fizica" (Biofizica moleculara) "magna cum laude".
August 1998 - September 1999
In urma unei competitii internationale, mi-a fost oferita o pozitia de cercetare (research officer) la University of Queensland (Brisbane, Australia). Conducatori de proiect au fost Prof. David J. Adams (Department of Physiology & Pharmacology) si Dr. Richard Lewis (Centre for Drug Design and Development). Finantarea a fost acordata de AMRAD-Melbourne.
July 2001 - July 2003
In urma unei competitii internationale, mi-a fost oferita o pozitia de cercetare (research officer) la Texas A&M University (College Station, Texas, USA). Seful grupului de cercetare a fost Prof. Hagan Bayley. Finantarea a fost acordata de Office of Naval Research (ONR), the U.S. Department of Energy, the Multidisciplinary University Research Initiative, the National Institute of Health, the Texas Advanced Technology Program.
-titluri academice;
Bachelor of science in Biofizica (Universitatea "Alexandru I. Cuza Iasi", Faculatea de Fizica)
Ph.D in Fizica (Biofizica moleculara)
(Universitatea "Karl-Franzens", Graz, Austria)
-pozitia ocupata;
-teme de cercetare;
Studierea proprietatilor biofizice ale membranelor excitabile (tehnica "patch-clamp", masurarea intra- si extracelulara a potentialului de membrana, tehnica current si voltage noise, masurarea impedantei biomembranelor excitabile in regim liniarizat)
Studierea canalelor ionice inserate in membrane lipidice artificiale (BLM). Constructia si studiul biosenzorilor bazati pe tehnologia "stochastic sensing".
Proprietatile biofizice ale transportului de substanta prin membrane artificiale si ale interfetei membrana artificiala - lichid.
Studierea caracteristicilor fizice ale nanoporilor artificiali realizati in filme polimerice
Fenomene de transport prin nanopori.
-programe, contracte;
"Studierea efectelor electro-conformationale si magneto-conformationale asupra proprietatilor canalelor ionice voltaj-dependente de sodiu si potasiu" Contractul No. 6186 / 2000-2002
"Influenta metalelor grele neurotoxice asupra proprietatilor biofizice ale membranelor biologice excitabile" Contractul No. 35252 / 2001-2002
-lucrari stiintifice publicate in ultimii 5 ani;
Richard J. Lewis, Katherine J. Nielsen, David J. Craik, Marion L. Loghnan, Denise A. Adams, Iain A. Sharpe, Tudor Luchian, David J. Adams, Trudy Bond, Linda Thomas, Alun Jones, Jodi L. Matheson, Roger Drinkwater, Peter R. Andrews, Paul F. Alewood - "Novel -conotoxins from Conus Catus discriminate among neuronal calcium channel subtypes", Journal of Biological Chemistry, 275:45, pp. 35335-35344, 2000
Tudor Luchian - "Coupling between a C-terminal peptide of a GIRK channel and its gating activity", Revue Roumaine de Chimie, 46 (10): 1155-1160 OCT 2001
Tudor Luchian - "The influence exerted by the 3 subunit on MVIIA binding to neuronal N-type calcium channels", BBA-Biomembranes, 1512:2, pp.329-334, 2001
Tudor Luchian, Bogdan Bancia, Catalin Pavel and Gheorghe Popa - "Biomembrane excitability studied within a wide-band frequency of an interacting exogenous electric field" Electromagnetic Biology and Medicine Vol. 21, No. 3, 287–302, 2002
Shin Seong-Ho, Luchian T, Cheley Steve, Braha Orit, Bayley Hagan. "Kinetics of a reversible covalent-bond-forming reaction observed at the single-molecule level" ANGEW CHEM INT EDIT 41 (19): 3707-3709, 2002 (reviewed in Nature Science update, 7 October 2003
Luchian Tudor, Shin Seong Ho, Bayley Hagan - "Kinetics of a three-step reaction observed at the single-molecule level" ANGEW CHEM INT EDIT 42, 1925-1929, 2003 (reviewed in C & En News, May 5, 2003
Luchian Tudor, Shin Seong Ho, Bayley Hagan - "Single-molecule chemistry with spatially separated reactants", ANGEW CHEM INT EDIT, in press, 2003
Luchian Tudor, Frangopol T. Petre "Electrical current-noise influence on the sub-threshold excitability properties of a biomembrane: friend or foe ?", Revue Roumaine de Chimie, in press, 2003
Tudor Luchian "New voltage-dependent processes ta the interaction between N-type calcium channels and synthetic conopeptides", Romanian Biophysical Journal’, 10:1-2, pp.75-82, 2000
Tudor Luchian, Richard J. Lewis, David J. Adams - "Modulatory effects of the subunit on -conotoxin binding to neuronal N-type calcium channels", Proceedings of the Australian Physiological and Pharmacological Society, New-Castle (Australia) 1999
Tudor Luchian - "Peculiar voltage-dependence processes at the interaction between N-type Ca2+ channels and synthetic conopeptides", Fourth General Conference of the Balkan Physical Union, Veliko Turnovo, 16P-016, 2000
Catalin Pavel, Bogdan Bancia, Tudor Luchian - "The vectorial effect of exogenous electric fields on excitable membranes", The 12-th BIOCHEMICAL BIOPHYSICAL BALKAN DAY "Molecular Biosciences in the PostGenomic Era" May, 10th-13th, 2001, Bucharest, Romania
Bogdan Bancia, Catalin Pavel, Tudor Luchian - "Resonant transfer of energy between an exogenous electric field and voltage-gated ionic channels", The 12-th BIOCHEMICAL BIOPHYSICAL BALKAN DAY "Molecular Biosciences in the PostGenomic Era" May, 10th-13th, 2001, Bucharest, Romania
Tudor Luchian, Bogdan Bancia, Catalin Pavel, Gheorghe Popa - 'International Conference Computational Mathematics And Modeling', 22-24 May 2002 Bangkok-Thailand
Shin Seong-Ho, Luchian T, Cheley Steve, Braha Orit, Bayley Hagan - "Reversible covalent chemistry in a protein-based nano-reactor at the single molecule level", Biophysical J. (a) 2003
- patente:
Bayley Hagan, Shin Seong-Ho, Luchian Tudor, Cheley Steve - "Stochastic sensing through covalent interactions", No. 60/379,527 and No. 60/450, 930, U.S. Patent pending, 2003
-cooperari;
Prof. Hagan Bayley (Oxford, England)
Dr. Francesco Moccia (Laboratory of Cell Biology, Napoli, Italy)